Edelris AS-MS Symposium

As part of Edelris’s 20th-anniversary celebrations, this symposium marked two decades of innovation in small-molecule drug discovery and highlighted recent advances in hit identification using AS-MS. It brought together leading voices from both academia and industry to share cutting-edge developments in tackling challenging drug targets.

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The fourth edition of the symposium opened with the presentation of new AS-MS perspectives, introducing CIAS-MS as a new technology offering the possibility to analyze by mass spectrometry, both the protein/ligand complex and its dissociated form. Various technical aspects of screening platforms dedicated to hit identification were discussed. The successes leading to the development of molecular tools to explore new targets were also presented.

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The program focused on the techniques developed by pharma and CRO organizations to implement AS-MS in their drug discovery process. Automated Data Processing was discussed and the synergy with other HTS technologies, particularly DELT, was emphasized.

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The program covered several aspects of AS-MS, featuring recent technological developments and exciting results on hot targets using various chemical matters including ultra-large libraries of peptides.

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The 1st Edelris Symposium highlighted the use of Affinity Selection-Mass Spectrometry (AS-MS) techniques to explore broad chemical spaces – biased collections, natural products, and large libraries.

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