Hepatitis B is still a major public health problem with more than 350 million people chronically infected worldwide, 20 to 40% of them being at risk of developing chronic liver disease, cirrhosis and hepatocellular carcinoma.

 Despite the existence of an effective preventive vaccine, the hepatitis B virus infection is still rampant in many countries, even developed ones, with an estimated 4.5 million cases of infection per year worldwide. Edelris and its partners Inserm and Poxel have identified FXR as a therapeutic target for HBV and discovered new compounds leading to a strong inhibition of viral DNA and viral antigen production.

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