Natural Product Chemistry
Therapeutic benefit of Natural Products
Since time immemorial, mankind has sourced the ﬂora and fauna around him to ameliorate disease. Whether starting points or end products in Pharma Research, Natural Products have usually showed original and evolved chemical structures as well as innovative ways to interact with living organisms towards a therapeutic benefit.
Programs based around NP structures
After an apparent fall from grace over the recent year, NP are now enjoying a growing interest, and Edelris, using its expertise of sophisticated and sensitive 3D molecules, has achieved on behalf of different clients several hit-to-lead/lead optimization programs based around NP structures.
Different NP classes have been progressed, including macrolactones and -lactams, polysaccharides, steroids, anthracyclines and polyfunctionnalized decalins.
Selected framework examples of Natural Products, NP derivatives and analogs prepared at Edelris